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											HOW BRAS CAUSE LYMPH STASIS 
											 
											
											
											(Lymph 
											Stasis is a slowing or stoppage of 
											the normal flow of a bodily fluid… 
											in this case lymphatic fluid) 
											
											
											AND BREAST CANCER 
											
											
											Sydney Ross SingerMedical Anthropologist
 
											
											When it was first announced back in 
											1995, the world was in shock. Bras 
											cause breast cancer! You’re kidding, 
											right? How could this foundation 
											garment that lifts and shapes the 
											breast be a source of disease? If 
											this was true, then why hasn’t this 
											information been announced before 
											now by mainstream medicine? It must 
											be false! 
											
											As medical anthropologists, we 
											examine the cultural causes of 
											disease. We became personally 
											involved in our own breast cancer 
											scare when Soma, my wife and 
											co-researcher, discovered a lump in 
											her breast. We were in Fiji at the 
											time, and she was pregnant. The 
											shock sent us back to the US in fear 
											and anxiety as we desperately tried 
											to figure out what she could have 
											been doing to her breasts to have 
											caused the lump. Soma was otherwise 
											a healthy person. It made no sense 
											that she would have breast cancer.
											 
											
											Looking for clues, we examined the 
											red marks and indentations in her 
											skin left by her bra. Most women 
											experience these same signs of 
											constriction. We had seen them every 
											day, but ignored them as a normal 
											part of bra-wearing. Now, they were 
											clues into what might have caused 
											Soma’s lump. 
											
											When you think about it, the first 
											thing to suspect when it comes to 
											foot disease are shoes. If you are 
											having breathing problems, the first 
											thing to suspect is smoking. And 
											when it comes to breast problems, 
											the first thing to suspect is the 
											bra. 
											
											We discovered that doctors knew bras 
											were causing breast cancer as far 
											back as the 1930’s. For example, Dr. 
											John Mayo, one of the founders of 
											the Mayo Clinic, wrote in the
											
											article “Susceptibility to Cancer” in the 
											
											1931 
											
											Annals of Surgery, 
											
											that “Cancer of the breast 
											occurs largely among civilized 
											women. In those countries where 
											breasts are allowed to be exposed, 
											that is, are not compressed or 
											irritated by clothing, it 
											
											(breast cancer) is rare.” A bra patent in 1950 stated, “Even in 
											the proper breast size, most 
											brassieres envelop or bind the 
											breast in such a fashion that normal 
											circulation and freedom of movement 
											is constricted. Many cases of breast 
											cancer have been attributed to such 
											breast constriction as caused by 
											improperly fitted brassieres.” 
											
											The problem caused by bras is due to 
											their constriction of the breasts, 
											particularly of the lymphatic 
											system, which is responsible for 
											eliminating toxins, cancer cells, 
											bacteria, viruses, and cellular 
											debris from the breasts. The 
											lymphatics are an essential 
											circulatory pathway of the immune 
											system. 
											(our lymphatic system consists of very fine spaces between the 
											cells of our tissues, where 
											lymphatic fluids flow, carrying 
											waste products from those cells to 
											lymph nodes, which test the fluid 
											for any possible diseases or cancer 
											cells, and then passes the fluid on 
											to where it goes into our 
											bloodstream, where other organs 
											clean out the waste products.)
											
											
											Constrict the microscopic, easily 
											compressed lymph vessels with tight 
											bras, and the result is lymph fluid 
											congestion in the breasts, or lymph 
											stasis, along with tissue 
											toxification 
											(imagine a garbage workers’ strike 
											in New York City). 
											This can cause breast pain and cysts 
											(which are filled with this lymph 
											fluid). Over time, as the breasts 
											progressively become toxic from 
											impaired lymphatic drainage, cancer 
											could result.  
											
											Realize that the lymphatic system is 
											our immune system’s circulatory 
											pathway leading from the tissue 
											spaces 
											
											
											(interlaced 
											between our body cells) to lymph nodes, 
											(we have lymph nodes all 
											over our body, and a whole bunch 
											surrounding our breasts) 
											
											which screen the lymph for signs
											
											(looking for ‘markers’) that an immune response is needed. 
											The lymph fluid starts around the 
											cells and drains the tissue spaces 
											of fluid and any bacteria, viruses, 
											cancer cells, toxins, and cellular 
											debris. The nodes are factories for 
											white blood-cell production, to 
											fight any detected infections or 
											developing cancer cells. The lymph 
											ultimately returns to the blood 
											stream. 
											(Any) interfering 
											with this pathway results in lymph 
											stasis, a stagnation of the 
											lymph fluid that results in various 
											diseases, including cancer. 
											Sometimes this lymph stasis is 
											obvious to see, as with lymphedema 
											and swollen tissue 
											
											(and felt… like those painful breast 
											cysts). At other times, lymphedema could be 
											mild, but chronic and cumulative
											
											
											(occurring 
											often, and building up over time). 
											
											Recently, pathologists have 
											identified a new organ in the body 
											that medicine never realized 
											existed. Its proposed name is the “interstitium”, 
											and it consists of a lymph-fluid 
											filled space that surrounds cells 
											and flushes fluid to the lymphatics, 
											acting as a pre-lymphatic space. 
											This space was not previously 
											recognized because the method of 
											tissue examination 
											
											(used up until now) 
											
											destroyed it. Modern probes can
											
											(now… finally) 
											be inserted into living tissue 
											and observe this space. Cancer cells 
											travel through the interstitium
											
											
											(our body frequently makes our very 
											own cancer cells, but if they can be 
											carried away in the lymph, they will 
											be destroyed by our immune system), 
											making its flow 
											
											(lymphatic fluid flow) 
											important for cancer prevention and 
											recovery. Of course, obstructing the 
											interstitium with tight bras 
											(lymphatic flow is 
											stopped from flowing with only 
											slight pressure on the skin) 
											would impair lymph flow, causing 
											lymph stasis 
											(which fails to remove cancer cells, 
											so they stay and develop into a 
											malignancy).  
											
											In addition to tissue toxification
											
											(making body tissues 
											become toxic from cellular wastes, 
											bacteria, etc.) from reduced lymphatic clearance
											
											
											(restricting the lymphatic fluid 
											from clearing the waste products out 
											the interstitium), 
											another problem caused by lymph 
											stasis is that cancer cells and 
											their immune markers cannot easily 
											get to the lymph nodes 
											(immune ‘markers’ are 
											what tell the lymph nodes which 
											antibodies are needed to fight a 
											disease). 
											This poor communication between the 
											tissues and the lymph nodes results 
											in reduced immune response to cancer
											
											(those cancer cells that we 
											ourselves are making), 
											and increased tumor growth, as 
											recent dermatology studies show. 
											Keep in mind that the breasts are 
											accessory skin organs.  
											
											In a 2014 paper in the journal 
											Clinical Dermatology, entitled, 
											“Lymphedema and subclinical 
											lymphostasis (microlymphedema) 
											facilitate cutaneous infection, 
											inflammatory dermatoses, and 
											neoplasia: A locus minoris 
											resistentiae”, the author explains, 
											“Chronic lymph stasis has numerous 
											consequences, including lipogenesis, 
											fibrosis, inflammation, 
											lymphangiogenesis, and 
											immunosuppression. For example, 
											lymphedema's disruption of immune 
											cell trafficking leads to localized 
											immune suppression, predisposing the 
											area affected to chronic 
											inflammation, infection (cellulitis 
											and verrucosis), and malignancy (angiosarcoma 
											and nonmelanoma skin cancer).”
											 
											
											In other words, lymph stasis in the 
											breasts reduces the ability of the 
											immune system to fight cancer cells. 
											Other researchers have discovered 
											that surgical damage to the 
											lymphatic system promotes tumor 
											growth by this mechanism. For 
											example, in the 2017 study in the 
											Journal of Dermatological Science, 
											called, “Surgical damage to the 
											lymphatic system promotes tumor 
											growth via impaired adaptive immune 
											response”, the authors conclude, 
											“These results strongly indicate 
											that surgical damage of the 
											lymphatic system may promote tumor 
											progression via impaired adaptive 
											immune response.” (even simple scar tissue can harm the function of the 
											lymphatic/immune system.) 
											
											A 2018 article published in the 
											Journal of Dermatological Science, 
											called, “Lymph stasis promotes tumor 
											growth”, echoes that 2017 study’s 
											findings.  
											
											·        
											
											
											These 
											findings come as no surprise to us 
											who for a long time have been aware 
											that alterations in regional 
											lymphatic flow may produce 
											dysregulation in skin immune 
											function and consequent oncogenesis
											
											
											(changing the natural function of 
											the immune system prevents it from 
											stopping oncogenesis… or the process 
											by which normal cells become cancer 
											cells, such as genetic mutation 
											during normal cellular division). 
											In fact, since 2002, our team has 
											held the view that lymphedematous 
											areas are immunologically vulnerable 
											sites for the development of 
											neoplasms as well as infections and 
											immune-mediated diseases. In recent 
											years, increasing evidence has 
											confirmed this assumption…. several 
											other cutaneous malignancies have 
											been reported to appear in the 
											presence of lymph stasis, such as 
											basal cell carcinoma, squamous cell 
											carcinoma, Merkel cell carcinoma, 
											melanoma, malignant fibrous 
											histiocytoma and lymphoma. Further 
											evidence of the oncologic 
											vulnerability of lymphedematous 
											regions ensues from the occurrence 
											of multiple skin malignancies in the 
											presence of lymph stasis. More than 
											20 basal cell carcinomas occurred on 
											a patient’s leg after recurrent 
											erysipelas and chronic lymphedema…. 
											In simple words, lymph stasis 
											functionally means 
											
											immune stasis 
											(if the lymphatic system is not functioning, the immune system 
											cannot function, which leads to 
											increased cancer development). 
											
											When regions of the skin (or 
											breasts) become immunocompromised
											
											(the 
											immune system is not able to 
											function properly) 
											it is termed an immunocompromised 
											cutaneous district, or ICD. In the 
											2014 article, “The immunocompromised 
											district in dermatology: A unifying 
											pathogenic view of the regional 
											immune dysregulation”, in the 
											journal Clinical Dermatology, 
											the author explains,  
											
											·        
											
											
											The factors responsible for 
											localized immune dysregulation are
											multifarious, 
											being represented by chronic 
											lymphatic stasis, herpetic 
											infections, ionizing or ultraviolet 
											(UV) radiations, burns, all sorts of 
											trauma (especially amputation), 
											tattooing, intradermal vaccinations, 
											and others of disparate nature (eg, 
											paralytic stroke, poliomyelitis). 
											Whatever the cause, in time an ICD 
											may become a vulnerable site, prone 
											to developing opportunistic 
											infections, tumors, or dysimmune 
											reactions (often of granulomatous 
											type), strictly confined to the 
											district itself… The pathomechanisms 
											involved in this sectorial immune 
											destabilization may reside in 
											locally hampered lymph drainage that 
											hinders the normal trafficking of
											
											
											immunocompetent cells.
											
											(many different conditions can render the lymphatic and immune 
											systems in an area ineffective, such 
											as UV radiation, tattoos, herpes, 
											lymphatic stasis, etc., and that 
											area can then become more vulnerable 
											to cancer.) 
											
											It should be explained that these 
											studies have not considered the bra 
											as a cause of lymph stasis of the 
											breasts. That conclusion is logical 
											from these skin studies. Tight 
											clothing impairs the interstitium 
											and the lymphatic vessels, which is 
											evidenced by seeing indentations and 
											marks in the skin. This compression 
											of the tissues impairs lymphatic 
											function and immune competence.
											 
											
											As research into the interstitium 
											and lymph stasis progresses, it is 
											hoped that pathologists can look up 
											from the microscopic view of the 
											human body to see the macroscopic 
											way we treat our bodies, which is 
											all conditioned by our culture. 
											Human beings are not merely 
											biological units. 
											(scientists often only see the microscopic world. Hopefully they 
											can step back and get the big 
											picture. They study the tree… but 
											ignore the forest. A damaged 
											lymphatic system can cause cancer… 
											but they are not seeing what causes 
											the damage to the lymphatic system?)
											
											
											Our biology is modified by our 
											culture and the things it leads us 
											to do, such as wear tight clothing 
											to alter body shape. You cannot 
											change shape without changing 
											lymphatic flow, since pressure must 
											be constantly applied to soft tissue 
											to achieve the desired shape. 
											 
											
											This pressure impairs lymph flow and 
											increases cancer risk, along with 
											the creation of other diseases of 
											constriction. For the breasts this 
											includes pain and lymph-fluid-filled 
											cysts. It also makes the breasts 
											heavy with lymph, resulting in 
											increased breast droop. Women who 
											stop wearing bras report rapid 
											improvement in breast health, 
											including reduced pain and cysts, 
											and a lifting and toning of the 
											breasts.  
											
											Clearly, further research is needed 
											to better demonstrate the impact of 
											chronic clothing constriction on the 
											body. In the meantime, women should 
											be warned about the hazards of tight 
											bras, and all people should consider 
											the tightness of their clothing and 
											undergarments.    
											
											References and further reading: 
											
											            1991 Harvard study (CC 
											Hsieh, D Trichopoulos (1991).
											
											
											
											Breast size, handedness and breast 
											cancer risk. 
											European Journal of Cancer and 
											Clinical Oncology 27(2):131-135.). 
											This study found that, 
											“Premenopausal women who do not wear 
											bras had half the risk of breast 
											cancer compared with bra users…” 
											
											            1991-93 U.S. Bra and 
											Breast Cancer Study by Singer and 
											Grismaijer, published in Dressed 
											To Kill: The Link Between Breast 
											Cancer and Bras (Second 
											Edition, Square One Publishers, 
											2018). Found that bra-free women 
											have about the same incidence of 
											breast cancer as men. 24/7 bra 
											wearing increases incidence over 100 
											times that of a bra-free woman. 
											
											            Singer and Grismaijer 
											did a follow-up study in Fiji, 
											published in Get 
											It Off! (ISCD 
											Press, 2000). Found 24 case 
											histories of breast cancer in a 
											culture where half the women are 
											bra-free. The women getting breast 
											cancer were all wearing bras. Given 
											women with the same genetics and 
											diet and living in the same village, 
											the ones getting breast disease were 
											the ones wearing bras for work. 
											
											            A 2009 Chinese study 
											(Zhang AQ, Xia JH, Wang Q, Li WP, Xu 
											J, Chen ZY, Yang JM (2009).
											
											
											
											[Risk factors of breast cancer in 
											women in Guangdong and the 
											countermeasures]. 
											In Chinese. Nan Fang Yi Ke Da Xue 
											Xue Bao. 2009 Jul;29(7):1451-3.)
											
											
											This article found that NOT sleeping 
											in a bra was protective against 
											breast cancer, lowering the risk 
											60%. 
											
											            
											
											
											 2011 
											a study
											was published, 
											in Spanish, confirming that bras are 
											causing breast disease and cancer. 
											 It found that underwired and 
											push-up bras are the most harmful, 
											but any bra that leaves red marks or 
											indentations may cause disease. 
											
											            2014 Lymphedema 
											and subclinical lymphostasis (microlymphedema) 
											facilitate cutaneous infection, 
											inflammatory dermatoses, and 
											neoplasia: A locus minoris 
											resistentiae. Clin 
											Dermatol. 2014 
											Sep-Oct;32(5):599-615. 
											
											            2015 
											
											
											 Comparative 
											study of breast cancer risk factors 
											at Kenyatta National Hospital and 
											the Nairobi Hospital 
											    J. Afr. Cancer (2015) 7:41-46.  This 
											study found a significant bra-cancer 
											link in pre-and post-menopausal 
											women. 
											
											            2016 
											
											
											 Wearing 
											a Tight Bra for Many Hours a Day is 
											Associated with Increased Risk of 
											Breast Cancer 
											
											    Adv Oncol Res Treat 1: 105.
											This is the 
											first epidemiological study to look 
											at bra tightness and time worn, and 
											found a significant bra-cancer link. 
											
											            2016 Brassiere 
											wearing and breast cancer risk: A 
											systematic review and meta-analysis  World 
											J Meta-Anal. Aug 
											26, 2015; 3(4): 193-205
											"This 
											systematic review and meta-analysis 
											aimed to evaluate the association 
											between 8 areas of brassiere-wearing 
											practices and the risk of breast 
											cancer. Twelve case-control studies 
											met inclusion criteria for review. 
											Although the meta-analysis shows 
											statistically significant findings 
											to support the association between 
											brassiere wearing during sleep and 
											breast cancer risk, evidence was 
											insufficient to establish a positive 
											association between brassiere 
											wearing (duration and type) and 
											breast cancer risk. A large-scale 
											epidemiological study is needed to 
											examine the relationship between 
											various forms of brassiere exposure 
											and breast cancer risk.” 
											
											            2016 
											
											
											Lymphatic Vessels, Inflammation, and 
											Immunity in Skin 
											Cancer Cancer 
											Discov. 2016 Jan; 6(1): 22–35.  
											
											            
											2017 Surgical 
											damage to the lymphatic system 
											promotes tumor growth via impaired 
											adaptive immune response Journal 
											of Dermatological Science April 
											2018Volume 90, Issue 1, Pages 46–51
											"These results 
											strongly indicate that surgical 
											damage of the lymphatic system may 
											promote tumor progression via 
											impaired adaptive immune response.” 
											
											            2018 Mechanical 
											forces in skin disorders  Journal 
											of Dermatological Science Available 
											March 2018 "Mechanical 
											forces are known to regulate 
											homeostasis of the skin and play a 
											role in the pathogenesis of 
											skin diseases….Acral 
											melanoma predominantly occurs in the 
											weight-bearing area of the foot 
											suggesting the role of mechanical 
											stress. Increased dermal stiffness 
											from fibrosis might 
											be the cause of recessive 
											dystrophic epidermolysis bullosa associated squamous 
											cell carcinoma.” 
											
											            2018 Lymph 
											stasis promotes tumor growth Journal 
											of Dermatological Science
											“[t]hese 
											findings come as no surprise to us 
											who for a long time have been aware 
											that alterations in 
											regional lymphatic flow may produce 
											dysregulation in skin immune 
											function and consequent oncogenesis. 
											In fact, since 2002, our team has 
											held the view that lymphedematous 
											areas are immunologically vulnerable 
											sites for the development of 
											neoplasms as well as infections and 
											immune-mediated diseases. In recent 
											years, increasing evidence has 
											confirmed this assumption.” 
											
											
											            
											
											2018 
											
											
											Structure and Distribution of an 
											Unrecognized Interstitium in Human 
											Tissues 
											Scientific Reports
											volume 8, 
											Article number: 4947 
											(2018). 
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